| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70b4adcb246898471965051b9ea8b3b1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-746
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L1-3014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-744
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01216 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-744
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 |
| filingDate |
2012-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9e43785b271c7b757602c8cabe5e188
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dc439deccf38220c8f25aea0f529f76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7c5d7fa92ae3214a9811c7b7aff3fea |
| publicationDate |
2014-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014234371-A1 |
| titleOfInvention |
Modified gram positive bacteria and uses thereof |
| abstract |
The present invention relates to a gram positive bacterium, preferably a lactic acid bacterium (LAB) or Bifidobacterium , with increased stress resistance and/or improved manufacturing, processing and/or storage characteristics. In particular, the invention relates to a gram positive bacterium which accumulate intracellular trehalose. The gram positive bacterium according to the invention lack trehalose 6-phosphate phosphorylase (TrePP) activity. The gram positive bacterium may further lack cellobiose-specific PTS system IIC component (ptcC) activity. The gram positive bacterium may further overexpress trehalose transporters. The invention further relates to compositions comprising such gram positive bacterium as well as methods and uses thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018051223-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10519418-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014227229-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10808014-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982228-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11384123-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793825-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9347036-B2 |
| priorityDate |
2011-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |