http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014227724-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c29324d6e4cbd44de52b26a0bb7e5ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46d6659ac4ce14165ae78eb9c154d6ea |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2012-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea8ed5c44668de7007b1c8d73cdd484b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d06ba09fd8c34edcd7b695db32b25485 |
publicationDate | 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2014227724-A1 |
titleOfInvention | Nucleic acid construct for use in screening for peptide antibody, and screening method using same |
abstract | The present invention provides a novel tool for simply screening a candidate molecule for an antibody and a method for screening a candidate molecule for an antibody using the tool. A nucleic acid construct includes: (x) an encoding nucleic acid of an antibody candidate, obtained by inserting an encoding nucleic acid of any peptide into an encoding nucleic acid of an antibody; (y) an encoding nucleic acid of a peptide tag; and (z) an encoding nucleic acid of an aptamer that is bindable to the peptide tag are used. When this nucleic acid construct is expressed, a complex of a fusion transcript of the encoding nucleic acids (x) to (z) and a fusion translation product of the encoding nucleic acids (x) and (y) is formed. When this complex and an antigen are brought into contact with each other, and the complex binding to the antigen is recovered, peptide that is bindable to the antigen and the encoding nucleic acid of the peptide can be identified from a transcript of an encoding nucleic acid of the any peptide in the complex. |
priorityDate | 2011-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.