| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ed7776bb635939b09253c8ad56fe0c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3099add4f7ba20ada88db7b115215eed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bc4c89d6053b42a2b91554f074a4dc5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-06 |
| filingDate |
2014-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0984e6590c2d1536c4fbea5b4272e6ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cae28c2ad7e252575ddc4ab6639f45c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b792e4fd8babb8a9850ef324cb5f1a1 |
| publicationDate |
2014-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014219992-A1 |
| titleOfInvention |
Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof |
| abstract |
Provided herein are methods of using modified matrix metalloprotease (MMP) enzymes that exhibit regulated activity in the presence of calcium. The methods include conditionally controlling the activity of the MMPs through the use of calcium to treat fibrotic diseases or conditions involving a component of the extracellular matrix (ECM). |
| priorityDate |
2013-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |