Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_531d4ee9f849effd35223dd90ea57011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ec6374e14f0c335fc74763168a31ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4da31fcc5b46320918dabe5f06770eaa |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
filingDate |
2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe9350b630fc5633d692cf569d2eb5de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6a1c62ac5f7e7ea5b0d73cd8c9051ab |
publicationDate |
2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014213559-A1 |
titleOfInvention |
Compositions and treatments for dystrophies |
abstract |
The present invention provides an inhibitor of intracellular protein degradation for use in the treatment and prevention of muscular dystrophy in a mammal. In particular, the invention provides an autophagy inhibitor and/or an inhibitor of the ubiquitin-proteasome system (such as a proteasome inhibitor) for use in the treatment and prevention of muscular dystrophy (such as congenital muscular dystrophy [e.g. MDC1A) and Duchenne muscular dystrophy [DMD]). The invention further provides corresponding methods of treatment and prevention of muscular dystrophy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019226858-A1 |
priorityDate |
2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |