| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_344d0ce2e01579ac06c4ab3e39de2c9c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-911
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-773
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-906
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-907 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 |
| filingDate |
2012-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34933e7f91c86d0cbb968bba484ef40c |
| publicationDate |
2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014212479-A1 |
| titleOfInvention |
Intraperitoneally-administered nanocarriers that release their therapeutic load based on the inflammatory environment of cancers |
| abstract |
In one embodiment, the invention provides a new design of nanocarrier compositions that release their therapeutic load specifically at intraperitoneal cancers' site. These nanocarriers are administered intraperitoneally and comprise a plurality of porous nanoparticulates that (a) are loaded with one or more pharmaceutically-active agents alone or in combination with imaging agents thus providing a theranostic value and (b) that are encapsulated by and that support a lipid bilayer which is disrupted upon contact with a reactive oxygen species generated within the environment of the cancer. In other embodiments, the invention provides methods of treatment and pharmaceutical compositions comprising nanocarriers as described herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11672866-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723920-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11344629-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9480653-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10500164-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115105584-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018369422-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3256110-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9579283-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10016365-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11207348-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019213270-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11547680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083705-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11071713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016044716-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779652-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10617672-B2 |
| priorityDate |
2011-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |