http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014206091-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676b80da7ac92b84e447a83fb1630ae1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-416 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2014-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cf0be7d7cad3a948bd5f7cf4c93b626 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9c34478c7ce7264a2c69ac53f23b9b7 |
publicationDate | 2014-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2014206091-A1 |
titleOfInvention | Cross-linking compositions and related methods of isotope tagging of interacting proteins and analysis of protein interactions |
abstract | An isotope labeled asymmetric cross-linker is provided for the detection of cross-linked peptides. A cross-linking and mass spectrometry strategy, referred to as isotope tagging of interacting proteins (iTIP), improves the specificity of detecting cross-linked peptides and accurate identification of the interacting peptide sequences via the incorporation of isotopic signatures that are readily observed in the MS/MS spectrum. Isotope tagged peptides can be identified using mass spectrometry based on doublet peaks in a spectrum. Spectra can be subjected to database search strategies available for the sequencing of linear or non-cross-linked peptides. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108459001-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10916331-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021072169-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016200681-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017156480-A1 |
priorityDate | 2013-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 318.