Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26c475bcbe0c24b485b6f37c45cd921f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-38663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C11D3-38681 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-54 |
filingDate |
2014-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c88941c83489b4e6d6ddc4e1532fa950 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f497364d9505923c20d910f60cc9171 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50174e7d5f02e5391dd4525da88130e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60bfb89bf7e5b777afd96d0fc2cc8877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0de6f1dbb984694fa6b6d688a4ddd208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_949e7b7e811f4aefa7de1f1860125984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c190f3db8abcc692f7e070c1f993a7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efbf906433437222d76c88c579626411 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c410b45024b988420cbd71cc5505081e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c71e3a14c2fb63818ef4e54f749baf63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d9dea014be5e4158763dc4b2c51f46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f09de0fbce228154294aa211973c0fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a007089f9924f740e44821e328d8d28a |
publicationDate |
2014-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014186868-A1 |
titleOfInvention |
Method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme |
abstract |
The stabilization of a hydrolytic enzyme in a liquid preparation is to be improved through a component that stabilizes the hydrolytic enzyme. This is accomplished by a method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme, comprising the following method steps: a) providing a hydrolytic enzyme (starting enzyme) and a component that stabilizes the hydrolytic enzyme and that comprises a reversible inhibitor of the hydrolytic enzyme; b) changing the amino acid sequence of the hydrolytic enzyme in at least one position, by substitution, deletion or insertion; c) determining the relative activity of the hydrolytic enzyme from step b) and the relative activity of the starting enzyme in a liquid preparation; d) selecting the hydrolytic enzyme that has a reduced relative activity by comparison with the relative activity of the starting enzyme. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11166478-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10731111-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016374364-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11427839-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11623966-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11680278-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016097405-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9695381-B2 |
priorityDate |
2011-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |