Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_122650eb52acea73f51909f275549e74 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate |
2013-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f57f30b25d2e8359bdd844215ba86ba4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62ca9ff88b0fdfcce2180fa615a67c83 |
publicationDate |
2014-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014186339-A1 |
titleOfInvention |
Compositions and methods for treating ocular diseases and conditions |
abstract |
The present invention relates to compositions and methods for prevention and treatment of ocular diseases and conditions, particularly glaucoma and ocular hypertension. The compositions and methods of the invention utilize immune-derived moieties that are specifically reactive against the bioactive lipid, sphingosine-1-phosphate, and its variants, which moieties are capable of decreasing the effective concentration of bioactive lipid being targeted. In one embodiment, the immune-derived moiety is a humanized monoclonal antibody that is reactive against sphingosine-1-phosphate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291684-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2759998-C2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114796213-A |
priorityDate |
2006-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |