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filingDate 2013-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014170162-A1
titleOfInvention Preservation of the neuromuscular junction (nmj) after traumatic nerve injury
abstract The invention relates to treatment and/or prevention of nerve injury. In one embodiment, the present invention provides a method of preserving the neuromuscular junction (NMJ) in an individual by administering a therapeutically effective dosage of a composition comprising an inhibitor of Wnt3a, and an inhibitor of MMP3 to the individual. In another embodiment, the present invention provides a method of stabilizing NMJ after nerve injury by inhibiting the WNT and beta-catenin signaling pathway and preserving agrin.
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priorityDate 2012-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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