| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33dfa2510a61c44d14c514c4d4d3ec1d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-252 |
| filingDate |
2014-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b7ca51edf7ff446216ccc2973fcc9a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889fde0124d9a0348aa97122cfa1b0b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9cf857a23a9a66244e5eec3726969d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f53370e05dc1024e6f7fa64c4de3d9b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0408494e18cc4cb02c488dc26ed06c1b |
| publicationDate |
2014-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014148587-A1 |
| titleOfInvention |
Crystalline 4′-epidaunorubicin hydrochloride and use thereof |
| abstract |
4′-epidaunorubicin hydrochloride is provided in a crystalline form which is stable and readily soluble. A process of producing the crystalline form includes crystallizing 4′-epidaunorubicin hydrochloride in a solvent system including (a) solvent A selected from C 1 and C 2 halogenated solvents and mixtures thereof, (b) solvent B selected from C 1 -C 5 straight and branched alcohols and mixtures thereof, and (c) solvent C selected from C 1 -C 5 straight and branched alcohols and mixtures thereof, wherein solvent C is selected to provide lower solubility to 4′-epidaunorubicin hydrochloride than solvent B. A method of producing an anthracycline using crystalline 4′-epidaunorubicin hydrochloride is also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015149001-A1 |
| priorityDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |