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publicationDate 2014-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014106058-A1
titleOfInvention Taste masked active pharmaceutical powder compositions and processes for making them
abstract A taste masked particulate pharmaceutical formulation include a core that comprises an active pharmaceutical ingredient; at least a partial nanoparticle material layer on the core that comprises a nanoparticle material with a median particle size not greater than 100 nm; a first polymer layer that is at least partially water soluble and a second polymer layer that is water insoluble. The active pharmaceutical ingredient is completely released in 30 minutes in the USP Dissolution Test. A process of making the particulate pharmaceutical formulation using sequential fluidized bed coating steps under controlled conditions is also described.
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