Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e64a8b536970dc037020659710d5f06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83dc1b53900fc90183141c6d9082f226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9174c6496948bb10e01bd9a16b5d1148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdc8f1723c9ef27b85010a526b0d0cb4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-50 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2012-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed3476ff53cc1e3921797dc5b6591cb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94c2b2d53c2470814f549664e3c332e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49a0dae14aeaccb3feda1d935069a0de |
publicationDate |
2014-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014072986-A1 |
titleOfInvention |
Amyloid protein oligomer-binding aptamer |
abstract |
An aptamer having a G-quartet structure and being at least one selected from the group consisting of the following polynucleotides, the aptamer having a binding ability to an amyloid protein oligomer: (1) a polynucleotide comprising a base sequence represented by any one of SEQ ID NO:1 to SEQ ID NO:18; (2) a polynucleotide comprising a base sequence that includes at least four sets of at least two consecutive guanosine nucleotides and in which one or several bases has been deleted, substituted, or added in a base sequence represented by any one of SEQ ID NO:18; and (3) a polynucleotide that is a multimer including the polynucleotide of (1) or (2) as a structural unit. |
priorityDate |
2011-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |