| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e56963b31b296ff7ca89ec39af684d0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_303c6b5d7cf5e63de2a36b35359cfb0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1117166c111be30ccb54005aeb26db2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f3204bc7ee7998f3aa89c9983498492
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a1c31c54eaed929da76f14c47c25570 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-27 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 |
| filingDate |
2011-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e503e5686bdc4b3513439959f50373fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f66d2460ac6e1c630e6e7a97b13fb20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aafa5f3da34ce519ca970b41e726ffa6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34c947db305a3a0ee2fb7e0305960e96 |
| publicationDate |
2014-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014058070-A1 |
| titleOfInvention |
C-terminal amidation of polypeptides |
| abstract |
There are provided compounds and methods for amidating the C-terminus of a polypeptide. The method include reacting a polypeptide which includes a C-terminal thioester or C-terminal selenoester with any one of a defined set of auxiliary molecules under conditions suitable to produce a polypeptide adduct which includes the auxiliary molecule chemically bound at the C-terminal of the polypeptide. In the subsequent step, the auxiliary molecule is removed from the C-terminal of the polypeptide adduct under conditions suitable to produce an amidated polypeptide. |
| priorityDate |
2010-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |