| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1c1d3001924100116dc65d6a03ea98e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C205-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-732
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-45 |
| filingDate |
2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_848a82beb8ff854f86778d7b9d2e5c67 |
| publicationDate |
2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014051874-A1 |
| titleOfInvention |
Method for producing five-membered ring-containing compound |
| abstract |
The present invention provides a method that allows production of stereospecific and asymmetrical five-membered ring-containing compounds serving as synthetic intermediates for formation of five-membered rings of prostaglandins and the like, with high yield and excellent stereoselectivity in terms of diastereoselectivity and enantioselectivity in a short process without requiring troublesome procedures such as optical resolution. The method for producing a five-membered ring-containing compound includes a cyclization step of condensing and cyclizing an α,β-unsaturated nitro compound represented by the following chemical formula (I) with a 1,4-butanedione compound, in the presence of a catalyst formed by a compound having a pyrrolidine ring and an optically active α-carbon relative to the nitrogen on the ring, in a water-insoluble organic solvent and/or a non-oxygen atom-containing water-soluble organic solvent so as to produce the five-membered ring-containing compound represented by the following chemical formula (II). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110475763-A |
| priorityDate |
2011-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |