| abstract |
Compounds of formula I: n n n n n n n n n n or formula II: n n n n n n n n n n n n or a pharmaceutically acceptable salt of formula I or formula II, wherein: n R 1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl; n R 2 is methyl or haloalkyl; n R 4 is hydroxyl, carbonyloxy, or carbonyldioxy; and n R 3 is aliphatic, aryl, aralkyl, or alkylaryl; and n R 5 , R 6 , R 7 and R 8 are each individually H, halogen, alkoxy, alkyl, haloalkyl, aryl, nitro, cyano, amino, amido, acyl, carboxyl, substituted carboxyl, or —SO 2 R 10 , wherein R 10 is H, alkyl, amino or haloalkyl; n provided that in formula I, R 5 and R 7 are not both H or R 6 is not H or methoxy; and in formula II that if R 4 is carbonyldioxy then R 7 is not methoxy. |