Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f84747e8d08b1023763356d0e7d1db68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_317ab2b1ed5a92da53a10b09b16f7bf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4b91fe9cd627d9d2efc9431e61b039f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-569 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate |
2012-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1cd3df046ca89f396b45f421e7fcd09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_add27a1ca93a71cb88da22f35a30828f |
publicationDate |
2014-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014037659-A1 |
titleOfInvention |
Snx9 as a novel biomarker for chronic inflammation and associated immunosuppresion and a new regulator of t cell receptor expression and function |
abstract |
The present invention relates to diagnostic and prognostic methods and kits for assessing chronic inflammation and associated immune-suppression. More particularly, the invention relates to the use of SNX9 (sorting nexin 9 protein) as a biomarker for chronic inflammation and associated immune-suppression, specifically, in subjects suffering from chronic inflammatory conditions. The invention further provides a prognostic tool for detecting regression or recurrence of the diseases and a powerful tool for assessing efficacy of a treatment. The present invention further provides SNX9 as an immunomodulator and therefore relates to methods for treating immune-related disorders by modulating SNX9 expression. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021063385-A1 |
priorityDate |
2011-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |