| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f96f5a8d18fbd16b055f8229afc46855
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4be79ae12eda41f75b9d521ab5da38d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36edee97e143bc8a93079a57e17e8a72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_091c51d89d0af71c90746cfc1d1bc882 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2011-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14d706990388e2f6c75a7cdb4a8c2b8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_004c8ca16b481740459d85abc0496cad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93f32b43326f548369b06fefadc92934
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bbf8a05a6f5d06f1f4efd30d25c179d |
| publicationDate |
2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014030709-A1 |
| titleOfInvention |
Biomarker for Detecting High-Altitude Adaptation and High-Altitude Pulmonary Edema |
| abstract |
Present invention relates to the Biomarkers for detecting high altitude adaptation and hypoxia responsiveness and the method thereof. The invention specifically relates to the Gene variants SNPIDs rs479200 and rs480902 in the first intron of EGLN1 (Prolyl Hydroxylase 2) gene as biomarkers for adaptation to high altitude and predisposition for high altitude pulmonary edema and hypoxia responsiveness using a novel integrative approach of phenotyping concepts of Ayurveda with population genetics, and disease genomics. More specifically, the C allele of SNP ID rs480902 and T allele of rs479200 of EGLN1 gene is more frequent in patients of HAPE and nearly absent in native highlanders. The present invention also provides primers and methods suitable for the detection of these allelic variants for the prediction of individual's adaptability to high altitude and hypoxia and/or the genetic analysis of the EGLN1 gene in a population. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10491819-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115976195-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111560428-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114381517-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114292909-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111676283-A |
| priorityDate |
2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |