| abstract |
A topical liquid agent for a nail and/or skin for prevention or treatment of dermatophytosis comprises a film-forming agent and a compound represented by the formula: n n n n n n n n n n wherein R 1 represents hydrogen, C 1-6 alkyl, or trifluoromethyl, R 2 represents hydrogen, C 1-6 alkyl, halogen, —COO(C 1-6 alkyl), or (CH 2 ) 1-3 COOR where R represents hydrogen or C 1-6 alkyl, R 3 represents hydrogen, C 1-6 alkyl, amino, trifluoromethyl, or OR where R represents hydrogen or C 1-6 alkyl, R 4 represents hydroxyl, R 5 represents hydrogen, C 1-6 alkyl, hydroxyl, or halogen, R 6 represents hydrogen, C 1-6 alkyl, trifluoromethyl, halogen, amino, —NR a R b , nitro, hydroxy-C 1-6 alkyl, —CONR a R b , —COO(C 1-6 alkyl), —COOH, —(CH 2 ) 1-3 COOR, or OR a where R represents hydrogen or C 1-6 alkyl, R a and R b each represent hydrogen, C 1-6 alkyl, or C 1-6 acyl, R 7 represents hydrogen, C 1-6 alkyl, —OR where R represents hydrogen or C 1-6 alkyl, or halogen, R 8 represents hydrogen, C 1-6 alkyl, hydroxyl, amino, or nitro, or a salt thereof. |