| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77d9bf55e6700374867763cc2c6acaff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22af0c923d7537d54c62e7b66d4dceed |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate |
2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63652a451183a0f53b748d6f43e36e3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adf129ec877fe4774d0089ca0ceae388
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_830826366a52cdd1f787c11f41e854e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b0739d5fbee32bc86ffbddb3ba0e98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9582ecb0b0f99800b7c2a865f78b2231 |
| publicationDate |
2014-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014024812-A1 |
| titleOfInvention |
Engineered intracellular sialylation pathways |
| abstract |
Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins. |
| priorityDate |
1999-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |