| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6958e93399b9f8aceffc365546914cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f90ae08102b7725b23841291df98938
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52316262ffde3218a6eb472a7fc20077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36a8a25d5dad5038d7eddb7306f32afc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37c7b510cfbe37eb42d6af8c117cb30b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-11 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-11 |
| filingDate |
2011-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e031636ebb84e3d637df610adcedf64e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_030603b9219615a0da1452c8b1de3ebc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31493473139caa1c59fa81ba2b6757c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faa463d2cdaf243a156070a91fd42de9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1d98d9aa4693955b05f89f7c95c089f |
| publicationDate |
2014-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014018578-A1 |
| titleOfInvention |
New method for the synthesis of rasagiline |
| abstract |
We have developed a new method for the synthesis of Rasagiline (Formula 1) based on the alkylation of trifluoroacetyl protected aminoindan. This protection enabled us to carry out an alkylation of aminoindan with a high yield and purity under very mild conditions with a wide range of reaction conditions and reagent selection. Considering the ease, purity and high yields of introducing and removal of the trifluoroacetyl group, this approach is a highly practical and economical way for the synthesis of rasagiline or its pharmaceutically acceptable salts. |
| priorityDate |
2011-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |