| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a6df5b976572a2881f7741037affdcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef1740ce111f5f26eab70a0dd2aaeb62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d09e530cccccafb95bf3525d7e08d659
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8e8ee2d7a1c87972c2d05b5ba00b661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_523409f720145382e5e117548ae6ae76 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-1836
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 |
| filingDate |
2011-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ee8d1b8ecc3ec8bf589fd16800ab257
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c7d2f31903ff313aadd56fcb909976f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0d6b9688d6125aaa01e6750dc7bf215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473e8743ef8471cb51fdf4ea6ba376a2 |
| publicationDate |
2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013345436-A1 |
| titleOfInvention |
method for preparing 2-(N-substituted)-amino-benzimidazole derivatives |
| abstract |
A method for preparing 2-(N-substituted)-amino-benzimidazole derivatives is provided, which comprises the following steps: (1) reacting a compound of 2-(N-protecting group)-O-aryl diamine with a compound of N-phenoxycarbonyl monosubstituted amine to obtain a compound of 2-(N-protecting group)-amino aryl urea; (2) in a suitable organic solvent, performing dehydrating cyclization reaction of the compound of 2-(N-protecting group)-amino aryl urea in the presence of an organic base and dichloro triphenylphosphine prepared by triphenylphosphine oxide with oxalyl chloride or diphosgene or triphosgene, or dibromo triphenylphosphine prepared by triphenylphosphine oxide with bromine, to produce a compound of 1-protecting group-2-(N-substituted)-amino-benzimidazole; (3) deprotecting the resulting compound of 1-protecting group-2-(N-substituted)-amino-benzimidazole to obtain the compound 2-(N-substituted)-amino-benzimidazole. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019213470-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512055-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7351851-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2789059-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9518011-B2 |
| priorityDate |
2010-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |