Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d26bb14ef61665355dc8b77b05424c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35455de230f9688e85a5afb026049a28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c71a802dc679d7bc6136de123d15dc55 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2012-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78ab16a4be7aaf37e319b5e4fcca42f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5471541724167df66246e749b000b9c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbcfe155cbe668b5020df8075233dfae |
publicationDate |
2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013345234-A1 |
titleOfInvention |
Fgfr and ligands thereof as biomarkers for breast cancer in hr positive subjects |
abstract |
The present invention describes methods for diagnosing, treating and determining the prognosis of breast cancer HR+ patient, the methods including detecting the amplification of one or more biomarkers comprising a FGFR ligand such as FGF3, FGF4, FGF19, and/or a FGFR, such as for example FGFR1 in a subject; determining an FGFR1 inhibitor for treating the subject based on the amplification of the one or more biomarkers in the subject; administering to the subject in need thereof the FGFR1 inhibitor and using the one or more biomarkers to indicate prognosis of the subject treated with the FGFR1 inhibitor. |
priorityDate |
2011-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |