http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013345234-A1

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filingDate 2012-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78ab16a4be7aaf37e319b5e4fcca42f3
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publicationDate 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2013345234-A1
titleOfInvention Fgfr and ligands thereof as biomarkers for breast cancer in hr positive subjects
abstract The present invention describes methods for diagnosing, treating and determining the prognosis of breast cancer HR+ patient, the methods including detecting the amplification of one or more biomarkers comprising a FGFR ligand such as FGF3, FGF4, FGF19, and/or a FGFR, such as for example FGFR1 in a subject; determining an FGFR1 inhibitor for treating the subject based on the amplification of the one or more biomarkers in the subject; administering to the subject in need thereof the FGFR1 inhibitor and using the one or more biomarkers to indicate prognosis of the subject treated with the FGFR1 inhibitor.
priorityDate 2011-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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