| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cd10993ac9afb36027684b03bbf666c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51f2f47dfae155008d3455c0336cdeac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe80af434308abc6cb622503b8e666a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21cb98a641e88664427b315aff908c53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34529d8432d781450b4739028fb853d3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2009-00872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2009-00895
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2009-00893 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-00804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-00802
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-00825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-062 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-008 |
| filingDate |
2013-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31e7526ac410bc8496cd12b2d84b0c3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcfbed17f5f49b491a8bb8bb4c1065d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f21cc275fd07cfdcc13f1917c7d6620
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d84156e9611a08b4097351a1162afde1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12115b71fdbf70a6340912a466621f94 |
| publicationDate |
2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013338650-A1 |
| titleOfInvention |
Nonlinear optical photodynamic therapy (nlo-pdt) of the cornea |
| abstract |
The embodiments include method of nonlinear optical photodynamic therapy of tissue including the steps of providing pulsed infrared laser light for two-photon excited fluorescence tissue exposure, and selectively focusing the pulsed infrared laser light within the tissue at a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. The invention is also directed to an apparatus for performing nonlinear optical photodynamic therapy of tissue including a pulsed infrared laser for providing two-photon excited fluorescence beam tissue exposure, a scanner for selectively and controllably moving the tissue and the beam relative to each other, and optics for selectively focusing the pulsed infrared laser light within the tissue at a point in a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10940042-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016175147-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018021172-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022339036-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020112823-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11207410-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11559433-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497403-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10010449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112351757-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020014411-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369515-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3319538-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11666481-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020099673-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10292865-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11260596-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11382795-B2 |
| priorityDate |
2011-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |