| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-06 |
| filingDate |
2013-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17ceb5bc63c44b3ab4d53b3ebf35a1d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_865a336823c15f176b5971c068317185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54989d1392e896857319092e69f8d3cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_366ae3c2a0ea1a3ba1e036904c9b0ff8 |
| publicationDate |
2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013338366-A1 |
| titleOfInvention |
Process for the preparation of pyrido [2,1-a] isoquinoline derivatives comprising optical resolution of an enamine |
| abstract |
This invention relates to a process for the preparation of pyrido[2,1-a]isoquinoline derivatives of the formula n n n n n n n n n n wherein R 1 , R 2 , R 3 and R 4 are defined in the specification, comprising the optical resolution of an enamine of the formula n n n n n n n n n n wherein R 1 is lower alkyl, in the presence of an optical active resolving agent to form an (S)-enamine salt of the formula n n n n n n n n n n wherein RCO 2 − is the conjugate base of the resolving agent. |
| priorityDate |
2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |