Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76a9c4244004ca63724cac71f66f7bda http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_319aa3eb09976d177d7c1adcee84eb8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1fe7343fbcb5a18124cfc657a7cce6a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_843781dc34d7aacf2b50d7cdf28cc904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b411d2e57299da3818a07a52c388de6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2301-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L101-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate |
2011-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_819e4f1550d24030ca40746954ef283e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_455d30f172768ade619c00aaadf78cc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f04afc2251e00ba98bdccafa295b42b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abdb47c2bce5d01bca82098f1307932b |
publicationDate |
2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013338099-A1 |
titleOfInvention |
Mercapto-modified biocompatible macromolecule derivatives with low degree of mercapto-modification and the cross-linked materials and uses thereof |
abstract |
The present invention discloses a mercapto-modified biocompatible macromolecule derivative with a low degree of modification. The mercapto-modified biocompatible macromolecule derivative not only maintains the initial structure, physiological function and biocompatibility as much as possible, but also allows the preparation of the biocompatible macromolecule cross-linked material with a low degree of cross-linking through the effectively chemical cross-linking with the introduced mercapto group. The present invention further discloses a disulfide-bond cross-linked biocompatible macromolecule material with a very low degree of cross-linking. The disulfide-bond cross-linked biocompatible macromolecule material not only maintains the initial structure, physiological function and biocompatibility of the biocompatible macromolecule as much as possible, but also effectively prolongs turn over and reduces the solubility of the biocompatible macromolecule in vivo, better meeting the requirements of various clinical applications. The present invention further relates to the application of the disulfide-bond cross-linked biocompatible macromolecule material in the field of medicine and pharmacy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113929975-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021194948-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020258775-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4032562-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114478829-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114316087-A |
priorityDate |
2010-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |