| abstract |
The present invention is directed to pharmaceutical compositions comprising antispasmodic C 4 -C 8 aliphatic-1,2-diols and C 4 -C 8 aliphatic-1,2,3-triols and their use to relieve the spasms associated with pain. These agents may be administered topically or orally and may be combined with anti-inflammatory agents such as a non-steroidal anti-inflammatory drug or a corticosteroid. Administration of the C 4 -C 8 aliphatic-1,2-diols and C 4 -C 8 aliphatic-1,2,3-triols with vitamin D 3 is indicated for conditions such as bone loss, weight gain and autoimmune diseases such as lupus and rheumatoid arthritis. |