| abstract |
The present invention provides 3-arylethynyl substituted quinazolinone compounds of formula (A) as potential anticancer agents against sixty human cancer cell lines. R 1 =H, OH, OCH 3 ; R 2 =H, OH, CH 3 ,OCH 3 , NO 2 ; R 3 =H, OH, OCH 3 , F, Cl; R 2 +R 3 =—OCH 2 O—; R 4 =H, OH, CH 3 , OCH 3 ; R 5 =H, OH, CH 3 , OCH 3 ; R 6 =H, OCH 3 . |