http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013302815-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec7aa9366c4867ba95ac5cd4fbbaec25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaf4038c815da5cd23d7f757dfc38f27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6958f7b5ae1d712a3176efb62e051c24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e16ffd11ee2be22dc3d4a94302a5cf0d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-142 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4738 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2011-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93dd99978bf43e8a8768f4b03ff67314 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dab4d9d1070e9d9d4688f19af29ac877 |
| publicationDate | 2013-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2013302815-A1 |
| titleOfInvention | Screening Method |
| abstract | The invention provides a polynucleotide comprising a reporter sequence operatively linked to a regulatory element of a gene selected from Bscl2, Srxnl, Cbr3, Ephxl, Nope, Cdknla, Perp, Pltp, Cgrefl, Ltb4r1, Btg2, Gpx2, Ltb4r2, Ddit4l, Fosl1, and Egr1, which regulatory element stimulates expression of the reporter sequence in response to a genotoxic agent or to an oxidative stress-inducing agent. The invention also provides a method of detecting a genotoxic or oxidative stress-inducing agent comprising subjecting a cell containing the polynucleotide of the invention to a test agent; and assessing the expression of the reporter sequence. The invention provides a method of detecting a genotoxic or oxidative stress-inducing agent comprising subjecting one or more cells that comprise a reporter sequence operatively linked to a regulatory element of a gene, which regulatory element stimulates expression of the reporter sequence in response to a genotoxic agent or to an oxidative stress-inducing agent, to a test agent, and assessing the expression of the one or more reporter sequences; wherein at least one cell subjected to a test agent comprises a polynucleotide comprising a reporter sequence operatively linked to a regulatory element of the Bsc12 gene. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11499139-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018118901-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016025510-A1 |
| priorityDate | 2010-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 886.