| abstract |
The present invention provides a single domain specific binding molecule having the structure n FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 n in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain. |