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filingDate 2013-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44f3b8242c3ca0f42fa8370ae28ea3ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54f5cc38a8830af494dd8dbbc2d48e85
publicationDate 2013-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2013289383-A1
titleOfInvention Magnetic Relaxometry using Brownian Randomization, Neel Relaxation, or Combinations Thereof
abstract The present invention can provide a method of determining the communication of substances between a first region and a second region of a patient's body. An example method according to the present invention can comprise: (a) introducing into the first region a plurality of superparamagnetic nanoparticles, having properties such that they undergo Brownian motion that randomizes the orientation of the nanoparticles according to a predetermined characteristic time; (b) after a time sufficient to allow transport of nanoparticles from the first region to the second region, subjecting the second region to an applied magnetic field of sufficient strength to induce magnetization of individual nanoparticles, and having a substantially uniform direction throughout the second region; (c) measuring the magnetic field of the second region at a plurality of times after ceasing application of the magnetic field; (d) analyzing the measured magnetic field to detect signals that correspond to decay of the magnetic field due to randomization of the nanoparticles' orientation by Brownian motion; (e) determining the presence of nanoparticles in the second region from the signals detected in step (d).
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017179731-A1
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priorityDate 2012-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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