Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9de410aa824908515188131d33dbb29 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-4277 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H05H1-00 |
filingDate |
2012-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ec148347dc4ee26c0167c2ce018b0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_563d324dfd8b352fe0298b250aef0ec5 |
publicationDate |
2013-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013289223-A1 |
titleOfInvention |
Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
abstract |
A pharmaceutically-active polymeric compound of the general formula (I), n Y-[Y n -LINK B-X] m -LINK B (I)n wherein (i) X is a coupled biological coupling agent of the general formula (II) nn Bio-LINK A-Bio (II)n wherein Bio is a biologically active agent fragment or precursor thereof linked to LINK A through a hydrolysable covalent bond; and LINK A is a coupled central flexible linear first segment of <2000 theoretical molecular weight linked to each of said Bio fragments; (ii) Y is LINK B-OLIGO; wherein (a) LINK B is a coupled second segment linking one OLIGO to another OLIGO and an OLIGO to X or precursor thereof; and (b) OLIGO is a short length of polymer segment having a molecular weight of less than 5,000 and comprising less than 100 monomeric repeating units; (iii) m is 1-40; and (iv) n is selected from 2-50. The compounds are useful as biomaterials, particularly, providing antibacterial activity in vivo. Also provided are biological coupling agents useful as intermediates in the preparation of the pharmaceutically-active polymeric compounds. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10588862-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10632075-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11612567-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10959954-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10945958-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11279729-B2 |
priorityDate |
2004-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |