http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013288380-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_063a1b324005ddc15e16e7529c6258c4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate | 2013-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1a010862ce835c3212c9e1db46f20bf |
publicationDate | 2013-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2013288380-A1 |
titleOfInvention | Method for detecting formation of g-quadruplex |
abstract | It is an object of the method of the present invention to specifically detect a G-quadruplex even in the presence of potassium ions. n The method of the present invention determines whether a target DNA forms a G-quadruplex using a phenomenon in which thioflavin T generates a strong fluorescence when reacted with the G-quadruplex in the presence of potassium ions. In the method of the present invention, a first sample solution containing potassium ions and a target DNA is retained under such conditions that a G-quadruplex is formed, followed by adding thioflavin T and measuring a first fluorescence intensity value. A second sample solution containing the target DNA is retained under conditions for the G-quadruplex to be destabilized, thioflavin T is added, a second fluorescence intensity value is measured, and it is determined that the target DNA can form a G-quadruplex if a difference between the first fluorescence intensity value and the second fluorescence intensity value is 0 or more. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112080549-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101954130-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018110980-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11033571-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020111753-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019240503-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019240504-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11175285-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105717081-A |
priorityDate | 2011-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.