Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1af8df51ce24ca931ae718fb747f6aa0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-4633 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5601 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-281 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-483 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-54 |
filingDate |
2013-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a434585735235937c9b2cd639ef80c65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73eeb1377286402fff2dc8f7fdcd96ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dd73c59075567f8af7768d1a5b48b44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce8eb78a75f06091f2cea9d0f6629da1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc6896c2e0cf172e6c7579f6adfb6ef4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb2cba55e83985a65a8caeebc2688c6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88785c6ac963fa26de604f9d07e92121 |
publicationDate |
2013-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013288345-A1 |
titleOfInvention |
Substrate probe, enzyme-activity detection method by a multi-dimensional nuclear magnetic resonance method and enzyme-activity imaging method |
abstract |
An object of the present invention is to provide a substrate probe capable of detecting enzyme activity with high accuracy and a method for detecting the enzyme activity by a multi nuclear magnetic resonance method using the substrate probe. Multi-dimensional nuclear magnetic resonance is performed by using a substrate probe, which is used for measuring enzyme activity by a multi-dimensional nuclear magnetic resonance method and characterized by containing a enzyme recognition site that is selectively recognized by an active-state enzyme, as at least one constitutional unit, and a group to which at least three nuclear magnetic resonance active nuclei each having a nuclear spin and a different resonance frequency are connected, being present specifically to the enzyme recognition, thereby detecting presence of the substrate probe and the enzyme activity. Alternatively, imaging of the enzyme activity is performed by a multi-dimensional nuclear resonance imaging method. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8773126-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10029021-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010225314-A1 |
priorityDate |
2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |