Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1821ab1c93a202311a485b203bc5a6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5569fcd649a6e915838b8164a6b37b05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c8f4982bb732717b64de77985f265c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abf6a7ccb035cf34c5695bdf3bd520ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75eca751241495c020648fdd32b9d776 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2541-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502769 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5302 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
2011-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbcedd03fa3fe1beb8260e317f0bf0d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0645a6b8b4e0078446d7c7fbcdd36e07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea49ec82cdfd6c0411f4d2821af3d3f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc93ac7a7882388a4828de66444a33f1 |
publicationDate |
2013-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013274113-A1 |
titleOfInvention |
Multiplex microfluidic device for selecting nucleic acid aptamers, and high throughput selection method for nucleic acid aptamers using same |
abstract |
The present invention relates to a multiplex microfluidic device for selection of nucleic acid aptamers and a method for high-throughput selection of nucleic acid aptamers using the same, and more particularly to a multiplex microfluidic device (SELEX lap-on-a-chip) that uses an improved multiplex platform in place of the development of an aptamer for a single target and to a method for high throughput selection of aptamers using the same together with high-throughput sequencing. A multiplex microfluidic device according to the present invention can simultaneously detect aptamers for a plurality of targets, and it can greatly increase the screening throughput and greatly shorten the process time compared to conventional multiplex techniques. Particularly, when a process for selecting aptamers is performed using the device of the invention together with a high-throughput sequencing method, the number of target binding/elution/amplification rounds can be greatly reduced, and the process can be performed in an automated manner. Thus, the device of the invention is highly useful. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11670400-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10546650-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9903859-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020160937-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017119904-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014303030-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294471-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10058276-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016059619-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10882045-B2 |
priorityDate |
2010-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |