Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f69aaa0aca013d832f58fe28b3fa795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fdfa4539c06962355e9e2bc7a9e0ee7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7365efb32db96243d00e5ed5572cb7e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2011-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3581e93ac239bffc6a6ee1b1dc4b652c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_666d240d0fd8059079b84ac3d5e2fb97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3da8c567497ee44cc63bcd7c56299a9 |
publicationDate |
2013-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013273076-A1 |
titleOfInvention |
Method for determining activators of excitatory synapse formation |
abstract |
The invention provides methods of screening a compound that can increase spine/excitatory synapse formation and/or numbers. The compound is identified by contacting Ephexin5 with a test compound and selecting the compounds that inhibit Rho GEF activity of Ephexin5. Additionally, the invention also provides methods for increasing spine/excitatory synapse formation and/or numbers by contacting a neuron with an Ephexin5 inhibitor. |
priorityDate |
2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |