Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65926bde90440f3178ef534c66bd7ce8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
filingDate |
2013-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1f71e14454a5afab061e02465dc53aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3aac2495c06710f8a77dab32248dd41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0581d0b441c68f47a293c5b37fceba92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de9bdb6ed51bd6ec3c2f70efaabc9395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582da205bac97680c8580de52dec5d0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d08757480ff7655131bc83fd2aeda88 |
publicationDate |
2013-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013259925-A1 |
titleOfInvention |
METHODS AND COMPOSITIONS TO TREAT CANCER USING BIFUNCTIONAL SRC 3 shRNA |
abstract |
The present invention includes compositions and methods of making and using an expression vector comprising a promoter and a nucleic acid insert operably linked to the promoter, wherein the insert encodes one or more short hairpin RNAs (shRNA) capable of inhibiting an expression of a SRC-3 gene via RNA interference, wherein the one or more shRNA comprise a bifunctional RNA molecule that activates a cleavage-dependent and a cleavage-independent RNA-induced silencing complex for reducing the expression level of the SRC-3. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633428-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633429-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497772-B2 |
priorityDate |
2012-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |