Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6604187e9cedc36387126e68d648757f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
filingDate |
2013-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30c6c19f7ee6a644a86c2f3a4477593b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a416240b19052ec54b275fbcdf3b37dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfb201e9ed674208ba197ab703f59197 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f026c94dbc7e3d35070da5ce18d4740 |
publicationDate |
2013-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013237556-A1 |
titleOfInvention |
Berberine alkaloid as a medicament for prevention and treatment of neural disease |
abstract |
The present invention is directed to method of preventing or treating neural disease or inhibiting accumulation of β-amyloid plaques in a subject by administering an effective dosage to the subject an agent (berberine) which inhibits the accumulation of β-amyloid- plaque, phospho-amyloid precursor protein (p-APP) and tau hyperphosphorylation in a mammalian brain. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112138007-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105497028-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015102380-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103989678-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103989678-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020077755-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017128291-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9650389-B2 |
priorityDate |
2012-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |