| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c7896469cc63c02f40e374501ac949c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec2cf2772a722c89d7cdeaf3f7f441cc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate |
2013-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f83c1fac520662aedd2b834852aa3fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f74a86faf0b34a6ee8e631991a091306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1923c6a9663205e68494d8fc48dedf02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a72ec17d6c66bf8241166aa846f7e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6fdf69430956eded12ed0b52c069390 |
| publicationDate |
2013-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013217634-A1 |
| titleOfInvention |
Peptides able to interfere with the inhibiting activity of mdm2/mdm4 heterodimer towards p53 and use thereof for cancer treatment |
| abstract |
The present disclosure concerns peptides able to interfere and in particular impair the inhibiting activity of MDM2/MDM4 heterodimer towards p53 and maintain the association between MDM4 and p53 so to restore the p53 oncosuppressive function in cancer cells harboring wild type p53 protein, directing its function specifically towards an apoptotic outcome. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105936646-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9902758-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017144016-A1 |
| priorityDate |
2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |