| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdcdee2b2e3d8aa591b37079afe11a86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1bc334266263952ba0c67497c2d145b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-02 |
| filingDate |
2013-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0155d7a5eb77f5b1414f70d568c142a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_298ed18f7ca5d6a8c23807a57d4a2cf0 |
| publicationDate |
2013-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013209523-A1 |
| titleOfInvention |
Amorphous Medicinal Fine Particles Produced By Pulsed Laser Ablation In Liquid And The Production Method Thereof |
| abstract |
The present disclosure is directed to an in-liquid laser-based method for fabricating a solution of fine particles of amorphous solid medicinal compounds, a solution of fine particles of amorphous medicinal agents made with the method, and fine particles made with the method. By using a target solidified via a phase transition process to covert an initial crystalline structure into an amorphous solid, technical difficulties with handling a hydraulically-pressed target are overcome. The laser-based ablation process produces amorphous solid medicinal compound fine particles, which improves the bioavailability and solubility of the medicinal compound. The improvement results from a combination of: disordered crystalline structure and enlarged relative surface area by particle size reduction. The laser based method may be carried out with ultrashort pulsed laser systems, or with UV nanosecond lasers. Results obtained with an ultrashort near IR laser and a UV nanosecond laser show formation of amorphous solid curcumin fine particles. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3505165-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109590478-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597817-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406684-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108779310-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629244-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011247234-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114632481-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11466140-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108159418-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8919007-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016236296-A1 |
| priorityDate |
2012-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |