| abstract |
The present invention provides a useful morpholino nucleic acid derivative for synthesizing a morpholino nucleic acid oligomer. The present invention provides a compound represented by the following general formula (1) or a salt thereof. n n n n n n n n n n Here, R 1 represents hydrogen, trityl and so on.n nR 2 represents an amide or an imine.n nR 3 represents a hydroxy group which may be protected by trialkylsilyl and so on, or a group represented by the following general formula (5):n n n n n n n n n n n (wherein X represents O or S, Y represents dialkylamino or alkoxy, and Z represents chlorine). |