Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bba710e7aaa56d8ab15a910fcd3dc5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0120c9791f3d1040b13056cb84debed4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5faa66d4993d4b03f107c0c29795234 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2011-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51b04e31cd898577ff8c64989876abed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d14f3be3401244ddf3a0ba310a828f0 |
publicationDate |
2013-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013196409-A1 |
titleOfInvention |
Targeted 2'-O-Methylation of Telomerase Non-Coding RNA |
abstract |
Processes and C/D box small nucleolar RNAs (snoRNAs) for altering telomerase activity and altering telomerase length are described. The processes of the invention involve the use of C/D box snoRNAs for targeted 2′-O-methylation modification of nucleotides in a pseudoknot region of the telomerase RNA. Depending on their position, the 2′-O-methylation modifications can cause an increase in telomerase activity and subsequent telomere lengthening or a decrease in telomerase activity and subsequent telomere shortening. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015017866-A1 |
priorityDate |
2010-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |