Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aedeb7af6c2ff48bfaf066ad40594a83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e53e64f3a72148fd1f704926bc7b72f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76739ab363cb5b367578ec7b31ad6bfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_286645a76054835e6611f420da115c18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd0bb7731f9cefdbee1975c582573c37 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2011-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33cbdf610292f00958030c5a41516b9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98b447f1eda3bb7d47af8408737e57c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6433d5922e3150bdb86c3953409664da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f936caa4a0fb56d5fada4f62c9fb124 |
publicationDate |
2013-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013189699-A1 |
titleOfInvention |
Ionic signal enhancement |
abstract |
Provided is a method of identifying an unknown nucleic acid comprising the steps of combining the unknown polynucleic acid with known nucleic acid reagents in a reaction chamber; producing a first quantity of protons from a polymerisation reaction when bases of one or more of the unknown nucleic acids are complementary to the bases of one or more known nucleic acids comprised within the known reagents; producing a second quantity of protons from a hydrolysis reaction of by-products of the polymerisation reaction with one or more enzymes; monitoring an electrical output signal derived from an ISFET exposed to the reaction chamber; and correlating changes in an output signal with said reactions between the unknown polynucleic acid and said known reagents to thereby identify the unknown nucleic acid. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11047004-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10344325-B2 |
priorityDate |
2010-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |