| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8eefd5ffa3ca69a9e4a936c39297380a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cabe01b7958425921805a949845a8ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6755dca546e9d5a5d6b488aac3107a27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_564388736955269806e7cb0a216326b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fe40eda58ae8c7c63ace8549d1591e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_742d14654e1eb06b5f5179930235b93a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-734 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0677
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2011-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2e90c736720ec96e92355bce07a66eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e7cbf86ff838391a8bd9284ef7809da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c7ef5e33f80652833932e9e514c50c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbcb64db2ea31193023c48880af41704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feb514b39cee948015cd29f829b0c614
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d0e13272dde2f701477f730eed6b49d |
| publicationDate |
2013-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013177986-A1 |
| titleOfInvention |
Pancreatic islet separation method, and protective solution for protecting pancreatic islet tissue |
| abstract |
The disclosed islet isolation method comprises: an injection step of injecting a preservation solution into the pancreatic duct of an excised pancreas; a preservation step of immersing the pancreas into an immersion fluid for preservation; a digestion step of breaking down the pancreas to provide pancreatic tissue; and a purification step of immersing the pancreatic tissue in a purification solution to provide islets. The digestion step consists of: an enzyme injection step of injecting an enzyme solution containing a digestion enzyme into the pancreas; a digestion initiation step of activating the digestion enzyme; a digestion termination step of inactivating the digestion enzyme; and a collection step of collecting the broken-down pancreatic tissue. The islet isolation method is characterized in that, by adding a neutrophil elastase inhibitor to the system before the digestion initiation step, the neutrophil elastase inhibitor is present inside the pancreas at the time point of starting the digestion initiation step. By using the above method and a protective solution which can be used in the method, islets having a size and shape suitable for transplantation can be obtained in high yields. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109666624-A |
| priorityDate |
2010-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |