http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013172567-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_648c9679dd9ec36125406a2dafa6bf7e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B32-50 |
filingDate | 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12cf961dadf682a1b4364b195d7d630f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3f58dec99381edcc1e22452db2726c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c418ff102408add6d3f2bffdac53589 |
publicationDate | 2013-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2013172567-A1 |
titleOfInvention | Methods of isolating (4-chloro-2-fluoro-3-substituted-phenyl)boronates and methods of using the same |
abstract | Methods of isolating a 4-chloro-2-fluoro-3-substituted-phenylboronate include adding carbon dioxide gas or carbon dioxide solid (dry ice) to a solution comprising a 4-chloro-2-fluoro-3-substituted-phenylboronate, an inert organic solvent, and at least one lithium salt to react the at least one lithium salt with the carbon dioxide gas or carbon dioxide solid (dry ice) and form a mixture comprising the 4-chloro-2-fluoro-3-substituted-phenylboronate, the inert organic solvent, and a precipitated solid. The precipitated solid may be removed from the mixture. Methods of using 4-chloro-2-fluoro-3-substituted-phenylboronates to produce methyl-4-amino-3-chloro-6-(4-chloro-2-fluoro-3-substituted-phenyl)pyridine-2-carboxylates are also disclosed. A 4-chloro-2-fluoro-3-substituted-phenylboronate produced by one of the methods of isolating a 4-chloro-2-fluoro-3-substituted-phenylboronate is also disclosed, wherein the 4-chloro-2-fluoro-3-substituted-phenylboronate may be obtained at a yield of greater than or equal to about 90%. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014100364-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10166533-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10112960-B2 |
priorityDate | 2011-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.