Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e14564c8dfaa020d889b263d46ad098 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b01a77903de4b50b0d6517bc1ad32f9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbc45553faee2f9788b7789ba09f2395 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4753 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 |
filingDate |
2011-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1883299319d30d22e1324d70869b8274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_189f9995166e65569045163c84862f4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8834dac70d6d97ad4a11895ff4abdc37 |
publicationDate |
2013-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2013171068-A1 |
titleOfInvention |
Hepatocyte growth factor fragments that function as potent met receptor agonists and antagonists |
abstract |
The NK1 fragment of hepatocyte growth factor (HGF) binds to and activates the Met receptor, a transmembrane receptor tyrosine kinase that plays a critical role in embryonic development and organ formation. The instant application discloses NK1 variant polypeptides which act as agonists or antagonists of HGF. Further disclosed are covalently linked NK1 variant polypeptides. Many of the disclosed variant polypeptides possess improved stability characteristics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113645989-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113226467-A |
priorityDate |
2010-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |