| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4135fd910972f34d1aab0031f128c5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edc3b0c5a5aaa580dc24baa988b172ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c97f477c24ce79736c108979e01397b2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1247
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
| filingDate |
2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3e00462a1202e1a340ba1dacad683a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7be24942678da6501ca237c6c677b1f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_468ae2a57adcaf49034862c77713b0e3 |
| publicationDate |
2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013130320-A1 |
| titleOfInvention |
Enzymes |
| abstract |
The invention relates to a nucleic acid polymerase capable of producing a non-DNA nucleotide polymer from a DNA nucleotide polymer template, said polymerase comprising amino acid sequence having at least 36% identity to the amino acid sequence of SEQ ID NO:1, wherein said amino acid sequence is mutated relative to the amino acid sequence of SEQ ID NO:1 at one or more residues of the thumb region, said residues selected from: amino acids 651 to 679 (patch 10A); wherein said amino acid sequence is mutated relative to the amino acid sequence of SEQ ID NO:1 at residue E664. In one embodiment said polymerase comprises the mutations Y409G and E664K. In one embodiment said polymerase comprises amino acid sequence corresponding to SEQ ID NO:12. The invention also relates to A nucleic acid polymerase capable of reverse transcribing a HNA nucleotide polymer into a DNA nucleotide polymer, said polymerase comprising amino acid sequence having at least 36% identity to the amino acid sequence of SEQ ID NO:1, wherein said amino acid sequence is mutated relative to the amino acid sequence of SEQ ID NO:1 at residue I521. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9834762-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017062965-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017067039-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10584319-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016097069-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9469862-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023056394-A1 |
| priorityDate |
2010-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |