| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7ebac14934be692eacb34b118613163
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63c0d66b5ffbd48d3d7a1934ae36e965
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef1f81f2a8c9e9c3f9b47af58d14b3c9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate |
2012-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e2eb88520f564912750011648f7839e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_723052a04154405bfd81c0623a3bb0e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0b9cff8621d79d841fb2c8140c7f9ad |
| publicationDate |
2013-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013123330-A1 |
| titleOfInvention |
Dual Targeted siRNA Therapeutics for Treatment of Diabetic Retinopathy and Other Ocular Neovascularization Diseases |
| abstract |
The present invention relates to compositions and methods for treating diabetic retinopathy and other ocular neovascularization diseases. In one embodiment, the composition comprises at least two different siRNA duplexes and a pharmaceutically acceptable carrier. One of the duplexes binds to an mRNA molecule that encodes VEGF, and the other binds to an mRNA molecule that encodes VEGFR2. In another embodiment, the composition further comprises an siRNA duplex that binds to an mRNA molecule that encodes TGFβ1. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015168347-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918720-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11160881-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021133931-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023288141-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015065773-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10369124-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023049807-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9227956-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2015253100-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11612660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447568-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10752896-B2 |
| priorityDate |
2011-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |