http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013109833-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24f1fd0c9c3a9687f506cf1465704843 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_714560022b5be978977d4a4665f92096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0284a3a0d4b6e5a6d77c03d6d7f7b866 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64 |
| filingDate | 2011-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b95ae8e63e9a4e110e8de3e2adea75c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea674216b69071fb11009538e23667e0 |
| publicationDate | 2013-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2013109833-A1 |
| titleOfInvention | Cyclic peptide compound or pharmacologically acceptable salt thereof and method for producing same |
| abstract | Provided are a cyclic peptide compound or a pharmacologically acceptable salt thereof capable of inhibiting parakeratosis of skin, and a method for producing the same. This method comprises subjecting a cyclic peptide compound of Formula (I): n n n n n n n n n n or a pharmacologically acceptable salt thereof, wherein Xaa 1 and Xaa 5 are each optionally substituted Ser, optionally substituted Thr, or optionally substituted Tyr; Xaa 2 is optionally substituted Ile, optionally substituted Val, or optionally substituted Leu; Xaa 3 and Xaa 4 are each optionally substituted Asn, optionally substituted Gln, optionally substituted Asp, or optionally substituted Glu; and R 1 is a group of Formula (II): n —CO—(CH 2 ) n —NH— (II),n n or Formula (III): n —NH—(CH 2 ) n —CO— (III),n n wherein n is the same as defined above, and in Formula (I), the linkage between Cys and Cys is a peptide bond or a disulfide bond, and the other linkages are peptide bonds,n to cyclization with a compound of Formula (IV): nn Cys-R 1 -Xaa 1 -Xaa 2 -Xaa 3 -Xaa 4 -Xaa 5 -Cys (IV),n n wherein, Xaa 1 , Xaa 2 , Xaa 3 , Xaa 4 , Xaa 5 , and R 1 are the same as defined above. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112426374-A |
| priorityDate | 2010-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 231.