http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013108699-A1

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filingDate 2010-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfa7912b8f47dc437bedbf60f22aa4ed
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publicationDate 2013-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2013108699-A1
titleOfInvention Highly dispersible granulate for the preparation of formulations of high dosage active substances and procedure for obtaining high dosage active substances thereof
abstract By mixing ibuprofen and a disaggregating agent, the invention involves using these components in a proportion ranging between 96% and 97% by weight for ibuprofen, and between 3% and 4% for the disaggregating agent, which may be Sodium croscarmellose, Crospovidone or Sodium carboxymethyl starch, as well as a mixture thereof. Following the mixing of the raw materials, the mixture is subjected to compaction, granulation and subsequent compression, in order to finally give the tablet a coating; this leads to a significant cost reduction and a significant reduction in the active principle release time, such that the pharmacological action is very fast in time.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112137966-A
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