| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cb03ff309c31e766cf428b88c1dd9a6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate |
2012-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8de6dd80aca30b36ca4e0a3d8c5b361a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38843563ebca42b5fece09a3faffe24b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eb5fdff910274c9c7ed740d8b0f0bde |
| publicationDate |
2013-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2013102595-A1 |
| titleOfInvention |
Treatment of cancers having k-ras mutations |
| abstract |
The present invention provides a method of treating a cancer associated with a K-ras mutation in a subject in need thereof. The method comprises the steps of: (1) identifying a subject with a cancer associated with a K-ras mutation; and (2) administering to the subject (i) an inhibitor of PI3 kinase and (ii) an HDAC inhibitor, wherein the PI3 kinase inhibitor and the HDAC inhibitor are administered in amounts which together are therapeutically effective. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9725461-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10543197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745321-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015203509-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8710219-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018085342-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8906909-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3053926-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10822336-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10894795-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11597732-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110642788-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261195-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11135205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11654136-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11234986-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3053926-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657032-B2 |
| priorityDate |
2011-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |